PARTNERS HUMAN RESEARCH COMMITTEE
116 Huntington Ave, Boston, MA 02116
Tel: 617-424-4100, Fax: 617-424-4199

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Oncology / Cancer-Related Research

The Brigham and Women’s Hospital and the Massachusetts General Hospital have agreed to rely on the Institutional Review Board of the Dana Farber Cancer Institute for review of certain research where the primary focus is cancer therapy OR in which the targeted population is only cancer patients OR where the research involves treatment of certain nonmalignant tumors with chemotherapeutic drugs. DFCI has agreed to rely on the Partners Institutional Review Board (Partners Human Research Committee) for review of certain research as well. This table is provided as guidance when questions arise about which IRB will provide review for specific categories of protocols.

RESEARCH INVOLVING…

IRB

Chemotherapeutic drugs to treat malignant tumors OR the following nonmalignant tumors:

  • Meningiomas
  • Schwannomas
  • Neurofibromas
  • Pancreatic cysts
  • Neuroendocrine pancreatic tumors

DFCI

Radiological diagnostic techniques directed at patients with cancer or follow-up of cancer therapy

DFCI

Cryotherapy or radioablation of malignant tumors

DFCI

Novel surgical approaches to cancer therapy

DFCI

Pain management/alternative medicine approaches to cancer therapy

DFCI

Cancer prevention in populations at high risk of cancer (e.g., pre-cancerous lesions)

DFCI

Treatment of the following nonmalignant tumors, with the exception of treatment involving chemotherapeutic drugs:

  • Meningiomas
  • Schwannomas
  • Neurofibromas
  • Pancreatic cysts
  • Neuroendocrine pancreatic tumors

PHS

Treatment of osteomas or pituitary adenomas

PHS

Treatment of warts/localized papillomas

PHS

Treatment of nonmalignant hematology

PHS

Populations with and without cancer (mixed populations); for example, studies of pain, infectious diseases, radiology/imaging, surgery, diagnosis

PHS

Nursing practice directed at patients with cancer

PHS

Collection of blood/tissue for genetic testing directed at cancer patients

PHS*

Health/medical records of cancer patients

PHS

Tissue samples derived from cancer patients

PHS*

Questionnaires/surveys directed at patients with cancer

PHS*

Tissue banks/repositories

TBD

Cancer prevention in the general population

PHS

*PHS IRB will report protocols falling within this category that it reviews to the DFCI IRB for purposes of reporting to NCI.

IRB Submission Instructions

DFCI Office for Human Research Studies (OHRS)

Partners Human Research Committee


Questions

DFCI: Sara Harnish / Jeff Clark, M.D.

PHS: Maria Sundquist / Libby Hohmann, M.D.

Version Date: August 31, 2010